IGBMC - Institut de génétique et de biologie moléculaire et cellulaire

Type : Rapport d’évaluation des unités de recherche

Campagne d'évaluation : 2011-2012 (vague C) - Publié le : 29/06/2012

Établissement(s) concerné(s) : Université de Strasbourg , Centre national de la recherche scientifique - CNRS , Institut national de la santé et de la recherche médicale - INSERM

Domaine(s) disciplinaire(s) de recherche : Sciences de la vie et de la terre (SVE) ; SVE2 - Productions végétales et animales (agronomie), biologie végétale et animale, biotechnologie et ingénierie des biosystèmes ; SVE5 - Neurosciences et troubles du système nerveux

Nom des équipes de l'unité : Single Cell Biophysics of Growth and Proliferation,Roles of retinoic acid in nervous system development and physiology,Cell physics, a joint Laboratory between IGBMC and ISIS,Cell cycle and ubiquitin signaling,Epigenetics and cell fate in early mamalian development,Mecano-genetic interplays and embryonic morphogenesis,Primordial germ cells? (PGC) ontogeny and pluripotency? instead of ?Primordial germ cells? (PGC) ontogeny?,Hematopoiesis and leukemogenesis in the mouse,Transcriptional regulatory networks and signalling in cancer,Genome expression and repair,From nuclear receptor action to novel paradigm for cancer therapy action,Chromatin and epigenetic regulation : Biological function of histone H3.3 variants,Integrin function and signaling in tissue morphogenesis, integrity and homeostasis,Pathophysiological function of nuclear receptor signaling,Molecular Biology of B cells,Molecular and cellular biology of breast cancer,Nuclear retinoic acid receptors phosphorylation and cross-talk with signaling pathways In vivo relevance of RARs phosphorylation : role in embryonic development and neurogenesis and deregulation in cancers,Protein networks and complexes regulating eukaryotic mRNA decay,Cell Biology of genome integrity,Dynamics of chromatin structure and transcription regulation,Molecular and cellular biology of cancer,Functional Epigenetics and Chromatin Regulation,Structural biology of epigenetic targets,Retinoic acid signaling pathways driving stem spermatogonia ontogenesis and differentiation,Biocomputing,Biomolecular Nuclear Magnetic Resonance,Large complexes involved in gene expression,Expression of genetic information,Evolutionary Inference in Biological Networks,Architecture of nucleoprotein systems by 3-D Electron Microscopy,Ribosomes,Action and inhibition studies of pharmaceutical targets,microRNA and long non-coding RNA diseases,Atherosclerosis and thrombosis,Neural development and evolution,Genetic mechanisms of neurodevelopmental disorders,Physiopathology of aneuploidy, gene dosage effect and Down syndrome,Opioid systems and brain function,Recessive ataxias,Pathophysiology of neuromuscular diseases,Fundamental and pathophysiological mechanisms implicated in recessive ataxia,Signal transduction in metabolism and inflammation,Polyglutamine expansion diseases: from pathomechanisms to therapeutic strategies,Differentiation and physiopathology of endocrine cells in the pancreas and intestine,Genetic and molecular analysis of early neurogenesis in Drosophila melanogaster,In vivo cellular plasticity and direct reprogramming,Forces and signals in tissue morphogenesis,Development of muscle and vertebrae

Mot(s) clé(s) : SVE2_1,SVE2_2,SVE2_3,SVE4,SVE3,SVE6